Gene description for RDX
Gene name	radixin
Gene symbol	RDX
Other names/aliases	DFNB24
Species	Homo sapiens
Experiment description of studies that identified RDX in Prostate cancer cells
1 Experiment ID 138 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name DU145 - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
2 Experiment ID 139 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name DU145 - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
3 Experiment ID 141 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name VCaP - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
4 Experiment ID 634 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
5 Experiment ID 963 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Sen Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
6 Experiment ID 964 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Res Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.13-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
7 Experiment ID 1113 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name VCaP- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
8 Experiment ID 1115 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name VCaP- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
9 Experiment ID 2324 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 31807237    Organism Homo sapiens Experiment description Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Authors Huang C, Hays FA, Tomasek JJ, Benyajati S, Zhang XA. Journal name J Extracell Vesicles Publication year 2019 Sample Prostate cancer cells Sample name Dul145 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 2325 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 31807237    Organism Homo sapiens Experiment description Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Authors Huang C, Hays FA, Tomasek JJ, Benyajati S, Zhang XA. Journal name J Extracell Vesicles Publication year 2019 Sample Prostate cancer cells Sample name Dul145 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 2326 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 31807237    Organism Homo sapiens Experiment description Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Authors Huang C, Hays FA, Tomasek JJ, Benyajati S, Zhang XA. Journal name J Extracell Vesicles Publication year 2019 Sample Prostate cancer cells Sample name Dul145 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 2327 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 31807237    Organism Homo sapiens Experiment description Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Authors Huang C, Hays FA, Tomasek JJ, Benyajati S, Zhang XA. Journal name J Extracell Vesicles Publication year 2019 Sample Prostate cancer cells Sample name LnCap Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
13 Experiment ID 2328 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 31807237    Organism Homo sapiens Experiment description Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Authors Huang C, Hays FA, Tomasek JJ, Benyajati S, Zhang XA. Journal name J Extracell Vesicles Publication year 2019 Sample Prostate cancer cells Sample name LnCap Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -